Treatment strategies for medulloblastoma and primitive neuroectodermal tumors
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چکیده
منابع مشابه
Treatment strategies for medulloblastoma and primitive neuroectodermal tumors.
Medulloblastoma and primitive neuroectodermal tumors (PNETs) are the most common malignant brain tumors in children. The concern for late sequelae of neuraxis irradiation and the obligation to improve disease-free survival in children who harbor malignant brain tumors has led to the additional provision of systemic chemotherapy to standard- and reduced-dose radiotherapy, as well as to the evalu...
متن کاملChemotherapy for Childhood Medulloblastoma and Primitive Neuroectodermal Tumors.
Medulloblastoma is the most common form of childhood brain tumor, and management has evolved over the past two decades. Chemotherapy is now an integral part of the treatment of the majority, if not all, patients with this disease. Medulloblastoma is a chemosensitive tumor, and recurrent disease will often respond to a variety of different chemotherapeutic agents. The use of higher-dose chemothe...
متن کاملPediatric Orbital Primitive Neuroectodermal Tumors.
PURPOSE To present the clinical, radiological, histopathological, immunohistochemical features and the follow-up of orbital primitive neuroectodermal tumors (PNETs) in pediatric patients along with a review of the literature. METHODS A retrospective analysis of all diagnosed cases of orbital PNET was done. Patients' ophthalmic findings, imaging, immunohistochemistry, metastatic work-up, treat...
متن کاملSupratentorial primitive neuroectodermal tumors in young children.
TO THE EDITOR: In the April issue of the Journal of Clinical Oncology, Timmermann et al suggest that radiotherapy plays a major role in the treatment of young children with supratentorial primitive neuroectodermal tumors (stPNET) and conclude that a delay in irradiation may compromise survival. Although stPNET are undoubtedly aggressive brain tumors and results of treatments are still disappoin...
متن کاملComputed tomography of primitive neuroectodermal tumors.
The primitive neuroectodermal tumor is a neoplasm of young individuals that occurs predominantly in the supratentorial compartment. It appears on computed tomography as a bulky mass, often with calcification with predominantly homogeneous enhancement but on occasion with cystic or necrotic areas. Cerebrospinal fluid seeding was observed in more than half the cases in our series. The patients ha...
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ژورنال
عنوان ژورنال: Neurosurgical Focus
سال: 1999
ISSN: 1092-0684
DOI: 10.3171/foc.1999.7.2.3